BOF 60
In common variable immune deficiency (CVID), all are
true except:
1- 30% have an associated lymphopaenia and
lymphadenopathy
2- IgA is virtually absent ,but IgG is usually
severely decreased but still detectable
3- Although defective cell mediated immunity is
documented but opportunistic infections due to this defect is rare in clinical
practice
4- In theory the presentation may be at any age ,but
usually in the 3rd decade
5- First degree relatives are at increased risk of IgG
subclass deficiency