Best of Five 52

 

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BOF: 52

A 50-year-old female has been referred for investigation of abnormal liver function tests. She consumes 52 units of  alcohol per week. On examination she is obese with mainly truncal obesity, with a moon face and a buffalo hump shaped deposit of fat across her shoulders. Her face is plethoric and there are numerous telangiectasiae. The abdomen is protuberant and there are striae. In this patient:

a)      The biochemical abnormalities do not return to normal with abstinence

b)      There is little relationship between the degree of liver damage and the plasma cortisol levels

c)      Urinary 17 – hydroxycorticosteroid levels are suppressed

d)      Plasma cortisol levels are suppressed

e)      Plasma ACTH levels are elevated

 

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