BOF: 3.58
A 27-year-old female presents with a history
of an itchy, blistering rash. On examination you note multiple small,
clustered vesicles over the elbows, knees and buttocks.
There are multiple excoriations around the
lesions.
You arrange a skin biopsy. The skin biopsy is
likely to reveal:
a) IgG
deposition on the surface of the keratinocytes in and around lesions
b) Granular
IgA deposits in dermal papillae of perilesional skin observed by direct
immunofluorescence
c) IgG and
complement C3 deposition in a linear band at the dermal-epidermal junction
d)
Immunoglobulin G and complement in a linear or granular bandlike pattern at
the basement membrane zone
e)
Infiltration of lymphocytes at the dermal-epidermal interface with
accompanying exocytosis and spongiosis in the epidermis
