BOF: 3.56
A 30-year-old male presents with a
history of feeling tired and passing dark urine. Five days prior to
presentation his general practitioner had treated him with co-trimoxazole, as
he had been complaining of a sore throat.
Investigations reveal:
Haemoglobin
8.4 g/dL (11.5 – 16.5 g/d)
Serum total
bilirubin 107 μmol/L (1 – 22 μmol/L)
The blood film shows multiple bite
cells
The most likely cause of this
patient’s present problem is:
a) Paroxysmal
cold haemoglobinuria
b) Autoimmune
haemolytic anaemia
c)
Glucose-6-phosphate dehydrogenase deficiency
d) Cold
agglutinin disease
e) Paroxysmal
nocturnal haemoglobinuria