BOF: 3.43
A 36-year-old female is known to have migraine. She is
usually able to get relief by using paracetamol. She had given up smoking for
years but has begun to smoke 20 cigarettes a day and now complains that
paracetamol no longer relieves her headaches.
This is because:
a)
Smoking reduces cerebral blood flow
b)
Nicotine is a competitive inhibitor of paracetamol
c)
Smoking induces liver enzymes
d)
Smoking reduces blood flow to the intestine and thereby reduces
absorption of paracetamol
e)
Smoking increases renal clearance of paracetamol
