Best of Five 2.25

 

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BOF: 42 (2.25)

A 55-year-old male who is known to have cirrhosis of the liver as a consequence of hereditary haemochromatosis presents with a rapid development of weight loss, anorexia, fever, ache in the right hypochondrium and ascites. On examination of the abdomen an enlarged, tender liver with an irregular edge is palpable.

Ultrasound scanning of the liver shows filling defects but serum alpha-foetoprotein is not raised. In this patient;

a)      Hepatocellular carcinoma is unlikely as the alpha-foetoprotein levels are not raised

b)      Ultrasound guided liver biopsy should be used to confirm the diagnosis of hepatocellular carcinoma

c)      Ascitic fluid cytology is likely to confirm the diagnosis of hepatocellular carcinoma

d)      Alpha-foetoprotein levels may be normal in patients with hepatocellular carcinoma

e)      Radio-isotope scanning should be used to confirm the diagnosis of hepatocellular carcinoma

 

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