If you find the material on this website useful, you will find that the two books ACES for PACES and KEYS to SUCCESS in Medicine complement the material on these sites and will enhance your studying and revision

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BOF: 169

A 55-year-old male is on azathioprine to maintain remission of Crohn’s disease. He has attended the cardiovascular risk clinic and has been started on allopurinol as he has been noted to have a high uric acid level.

He asks you whether he should take allopurinol and your reply is:

a)      There is no interaction between allopurinol and azathioprine

b)      Allopurinol potentiates toxicity of azathioprine

c)      Azathioprine potentiates toxicity of allopurinol

d)      Allopurinol reduces bioavailibilty of azathioprine

e)      Azathioprine reduces bioavailibilty of allopurinol

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