EMQ: 31
Haematological conditions
a)
Acute lymphoblastic leukaemia
b)
Chronic lymphocytic leukaemia
c)
Chronic myeloid leukaemia
d)
Acute myeloid leukaemia
e)
Polycythaemia rubra vera
f)
Primary thrombocythaemia
g)
Myeloma
h)
Hodgkin’s lymphoma
i)
Non-Hodgkin’s lymphoma
j)
Myelofibrosis
1)
A 76 year old male presents with pain his chest and back. Chest x-ray
shows multiple rib fractures, x-ray of his spine shows wedge compression of
his lumbar vertebrae. His ESR is very high , calcium levels are elevated and
there is Rouleaux formation on his blood film
Answer: g)
Myeloma
Myeloma refers
to malignant disease of the plasma cells in the bone marrow
2)
A 60 year old male presents with a history of fever and tiredness. On
examination he is noted to have splenomegaly.
Hb 9.0 g/dL
WBC 66 x109/L
60%
lymphocytes
Platelets 120
x109/L
Answer: b)
Chronic lymphocytic leukaemia
Chronic
lymphocytic leukaemia is a chronic haematalogical malignancy of excessive
proliferation of lymphocytes B rather than T
3)
A 16 year old male presents with a history of fever and bleeding gums.
On examination he is found to have lymphadenopathy and hepatosplenomegaly.
Hb 8.8g/dL
WBC 20 x109/L
Platelets 56
x109/L
Blood film
show multiple lymphoblasts
Answer: a)
Acute lymphoblastic leukaemia
An acute haematalogical
malignancy of proliferating abnormal lymphoblastic white cells that infiltrate
the body; marrow, blood, lungs, central nervous system
4)
A 54 year old male presents with a history of feeling tired and weak.
On examination there are multiple bruises on his shins. There is
hepatosplenomegaly.
Hb 9.3 g/dL
WBC 45 x109/L
Platelets 45
x109/L
Blood film
shows multiple blast cells
Answer: d)
Acute myeloid leukaemia
Acute haematalogical
malignancy of proliferating abnormal myeloid white cells the infiltrate the
body; marrow, blood , lungs , central nervous system
5)
A 60 year old male presents with a history of tiredness and pain in his
legs on walking. On examination you note that his face looks plethoric. There
is splenomegaly
Hb 20 g/dL
WBN 8.0 x109/L
Platelets 500
x109/L
Answer: e)
Polycythaemia rubra vera
Polycythaemia
rubra vera refers to a clonal stem cell disorder where there is proliferation
of all progenitor cells due to a genetic failure of apoptosis
