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BOF 44
The complement system, all are true except:
1-the classical pathway can be activated by IgG immune
complexes
2-properdin deficiency is usually X linked
3-deficiency of late complements components is
associated with disseminated Neisseria infection
4-SLE may be induced by congenital deficiency of the
early complements components
5-C1 esterase inhibitor deficiency is autosomal
dominant and the defect is qualitative in 90% of cases
Answer 5
1-or IgM. IgA activates the alternative pathway
2-and hence family tree is important in the male
relatives
3-true……..including recurrent meningitis
4-true….? may be due to inability to remove immune
complexes
5-fasle 10% only is of qualitative defect. The
majorities are of a quantitative defect
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