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 Answer BOF 36

 

   

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BOF 36
Radionuclide bone scan, all are true except:
1-utelizes IV injection of 99mTc-biphsphonate and detected by a gamma camera
2-early post injection images reflect increased vascularity as in Paget’s disease or inflamed synovium
3-delayed images reflect increased bone remodelling process.
4-paticularly useful in the assessment of local painful skeletal areas with normal or inconclusive plain radiographs
5-extremely useful in the assessment of multiple myeloma

Answer 5
1-as the isotope is taken by body bones
2-also in primary and secondary bone tumours
3-as the Tc-biphosphonate later localizes to areas of bone remodelling. These LATE images usually taken after few hours
4-true, the main indication in general
5-false, it depends on the osteoblastic activity which is inhibited in MM, so it is not useful here, only if complicated by fractures
Remember: although bone scan has a high sensitivity, it extremely lacks specificity and lacks high anatomical resolution

 



 

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