If you find the material on this website useful, you will find that the two books ACES for PACES and KEYS to SUCCESS in Medicine complement the material on these sites and will enhance your studying and revision

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ACES for PACES

Medical Revision

Clinical Skills Blogspot

Web ydr.org.uk acesforpaces.com medicalrevision.org

BOF: 32

Which of the following acts on the CD 20 antigen ?

a)   Infliximab

b)   Adalilumab

c)    Tratuzumab

d)   Rituximab

e)   Abciximab

Answer: d)

Rituximab

ü  Antibody directed against the CD 20 antigen

ü  Effectively eradicates CD20+ cells several distinct mechanisms, including complement-dependent cytotoxicity (CDC), antibody-dependent cellular cytotoxicity (ADCC) and apoptosis

Uses

ü  Non Hodgkin’s lymphoma

ü  Chronic lymphocytic leukaemia

ü  Rheumatoid arthritis

ü  Renal transplant rejection

Revision Tip

Revise non Hodgkin’s lymphoma KEYS to SUCCESS in Medicine page 397-399

Chronic lymphocytic leukaemia KEYS to SUCCESS in Medicine page 402-404

 

 

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