Answer BOF 2.14

 

   

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BOF: 2.14

A sixty-year-old male presents with a history of difficulty in walking. On examination of his eyes you note that his pupils are small and irregular. They do not react to light but react to accommodation. He also has bilateral ptosis and has wrinkling of his forehead. The abnormality that this patient has is:

a)      Holmes-Adie pupil

b)    Argyll-Robertson pupil

c)      Horner’s syndrome

d)      Relative afferent pupillary defect

e)      Myasthenia gravis

Answer:

b)

The Argyll-Robertson  pupil is thought to be due to a lesion in the tectum of the midbrain in proximity to the oculomotor nuclei.

The pupils are small and irregular and do not react to light but react to accommodation. Bilateral ptosis and wrinkling of the forehead due to overcompensation by the frontalis muscle suggests tabes dorsalis.

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