BOF 24
C reactive protein (CRP) and ESR, all are true except
1-CRP as an acute phase reactant, closely mirrors the
degree of inflammatory processes
2-CRP is the single most useful direct measure of the
acute phase responses (APR)
3-ESR is an indirect measure of the APR
4-ESR is characteristically very low in hear failure
and sickle cell disease
5-in SLE, the ESR and CRP are high during a relapse
Answer 5
1-as it rises rapidly and falls rapidly and hence
reflects the degree of the APRs
2-true as it rapidly rises from a low to high levels
in acute inflammatory process and closely mirrors the degree of inflammatory
3-true as in cases of improvement in the APR, the CRP
normalizes rapidly while the ESR LAGS behind for a variable period of time
4-and in PRV also, so in these cases we measure the
plasma viscosity as a measure of APR (remember in PRV there is florid APR yet
the ESR is very low)
5-the CRP is elevated in the presence of infection of
trauma in SLE, other wise in acute flare ups it is normal …a useful CLUE!!
