If you find the material on this website useful, you will find that the two books ACES for PACES and KEYS to SUCCESS in Medicine complement the material on these sites and will enhance your studying and revision

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BOF: 23

A 62 year old male has been started on finasteride for management of benign prostatic hyperplasia

Which one of the following adverse effects would you warn him about?

a) Gynaecomastia

b) Postural hypotension

c)  Oedema

d) Palpitations

e) Chest pain

Answer: a)

Finasteride

ü  Synthetic antiandrogen

ü  Inhibits type II 5-alpha reductase

ü  Prevents conversion of testosterone to dihydrotestosterone (DHT)

Adverse effects

RAG

ü  Impotence

ü  Ejaculation disorders

ü  Decreased volume of ejaculate

ü  Decreased libido

ü  Testicular pain

ü  Gynaecomastia

IS

ü  Hypersensitivity

ü  Urticaria

 

 

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