A 20-year-old male presents
with bleeding oesophageal varices. On examination he has Kayser- Fleischer rings
in the cornea. The inheritance of this disorder is:
a)Autosomal dominant
b)Autosomal recessive
c)X-linked recessive
d)X-linked dominant
e)Polygenic inheritance
Answer:
b)
This patient has Wilson’s
disease, which is inherited in an autosomal recessive fashion due to a mutation
on the long arm of chromosome 13
